College football Week 4 features an exciting lineup of seven matchups between Top 25 teams.
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The headliner is the No. 4 Ohio State vs. No. 9 Notre Dame game on Saturday evening.
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Ohio State's QB Kyle McCord and WR Marvin Harrison Jr. will challenge Notre Dame's defense led by DB Thomas Harper.
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The game between No. 19 Colorado and No. 11 Oregon adds intrigue to the Pac-12, with Colorado's QB Shedeur Sanders facing off against Oregon's QB Bo Nix.
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Colorado will be without star WR/CB Travis Hunter, which could impact the game's outcome.
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No. 25 UCLA takes on No. 10 Utah in another Pac-12 matchup, featuring freshman QB Dante Moore for UCLA and a question mark at QB for Utah.
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No. 15 Oregon State battles No. 24 Washington State in what some consider the true Pac-12 championship game.
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Ole Miss faces Alabama in an SEC opener with both teams looking to make a statement.
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The early window game of No. 3 Florida State vs. No. 23 Clemson promises an exciting ACC showdown.
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The battle between No. 22 Iowa and No. 7 Penn State showcases two undefeated Big Ten teams with strong defenses.
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